Drug Delivery Compounds
Lipids
Di(heptadecan-9-yl) 8,8'-((3-(dimethylamino)propyl)azanediyl)dioctanoate
Registry Number 2985009-50-3
100 mg/$5,000
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
Heptadecan-9-yl 8-((2-hydroxyethyl)(6-oxo-6-(undecyloxy)hexyl)amino)octanoate
O-11182 (SM-102; Lipid 8)
Registry Number 2089251-47-6
100 mg/$5,000
Reference: Molecular Therapy, 2018, 26, 1509-1519 (Lipid 8)
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-nonyloxy)-8-oxooctyl)amino)octanoate
O-3062 (Lipid 5)
100 mg/$5,000
Registry Number 2089251-33-0
Reference: Molecular Therapy, 2018, 26, 1509-1519 (Lipid 5)
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
((4-Hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate)
O-11676 (ALC-0315)
Registry Number 2036272-55-4
100 mg/$5,000
Reference: WO2019202035A1 (ALC-0315)
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
(6Z,9Z,28Z,31Z)-heptatriacont-6,9,28,31-tetraene-19-yl 4-(dimethylamino)butanoate
Registry Number 1224606-06-7
O-8640
100 mg/$1,500 (>98% UHPLC-CAD)
Dlin-MC3-DMA also known as MC3, is one of the most utilized cationic lipids that is used for making Lipid Nano-Particles (LNPs). These lipids, can form nanoparticles that can encapsulate and deliver siRNA, mRNA, DNA or small molecules into the cytoplasm and represent the most advanced delivery platforms for systemic administration of active molecules.
GMP Grade now available please email for price: sales@organixinc.com
References:
Jayaraman M et al. “Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo.” Angew Chem Int Ed Engl. 2012, 51(34), 8529.
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
3,6-bis(4-(bis(2-hydroxydodecyl)amino)butyl)piperazine-2,5-dione
CAS Number N/A
O-8744
100 mg/$3,900
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
3-(2,2-di((9Z,12Z)-octadeca-9,12-dien-1-yl)-1,3-dioxolan-4-yl)-N,N-dimethylpropan-1-amine
2,2-dilinoleyl-4-(4-dimethylaminopropyl)-[1,3]-dioxolane
CAS Number 1217306-46-1
O-10574
100 mg/$1,500
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
Bis(3-pentyloctyl) 9-((4-(dimethylamino)butanoyl)oxy)heptdecanedioate
O-10461
Registry Number 1443522-24-4
100 mg/$5,000
Reference: WO2013/86354
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
(6Z,9Z,28Z,31Z)-heptatriacont-6,9,28,31-tetraene-19-yl 4-(dimethylamino)butanoate
13C3 Labelled-MC3
O-8640-13C
2 mg/$5,000
10 mg/$19,500
Dlin-MC3-DMA also known as MC3, is one of the most utilized cationic lipids that is used for making Lipid Nano-Particles (LNPs). These lipids, can form nanoparticles that can encapsulate and deliver siRNA, mRNA, DNA or small molecules into the cytoplasm and represent the most advanced delivery platforms for systemic administration of active molecules.
References:
Jayaraman M et al. “Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo.” Angew Chem Int Ed Engl. 2012, 51(34), 8529.
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-nonyloxy)-8-oxooctyl)amino)octanoate
O-11480 (13C - Labeled Lipid 5)
2 mg/$5,000
10 mg/$19,500
Reference: Molecular Therapy, 2018, 26, 1509-1519
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
Di((Z)-non-2-en-1-yl) 8,8'-((2-((2-(dimethylamino)ethyl)thio)acetyl)azanediyl)dioctanoate
O-11280
100 mg/$5,000
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
Di((Z)-non-2-en-1-yl) 8,8'-((2-((2-(dimethylamino)ethyl)thio)carbonyl)azanediyl)dioctanoate
O-10380
100 mg/$5,000
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
di((Z)-non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate
Registry Number 1351586-50-9
O-8670
100 mg/$5,000
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
dimethyl (9Z,28Z)-19-((4-(dimethylamino)butanoyl)oxy) heptatriaconta-9,28-dienedioate
Registry Number 1351586-50-9
O-8648
100 mg/$5000
500 mg/$19,500
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
(6Z,9Z,28Z,31Z)-heptatriaconta-6,9,28,31-tetraen-19-yl 3-(dimethylamino)propanoate
Registry Number 1221271-55-1
O-3082
100 mg/$1,500
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
2-(2,2-di((9Z,12Z)-octadeca-9,12-dien-1-yl)-1,3-dioxolan-4-yl)-N,N-dimethylethan-1-amine
CAS Number 1190197-97-7
O-7781
100 mg/$1,500
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
1,1'-((2-(4-(2-((2-(bis(2-hydroxydodecyl)amino)ethyl)(2-hydroxydodecyl) amino)ethyl)piperazin-1-yl)ethyl)azanediyl)bis(dodecan-2-ol)
Registry Number 1220890-25-4
O-7788
100 mg/$3,900
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
GalNAc
GL6-based LNPs exhibit significant liver editing capability from 5% to 61% in the NHP model and resulted in an 89% reduction in ANGPTL3 protein in the blood for 6 months after administration.
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
GL6 (O-13287)
CAS# N/A
Tri-GalNAc (Cbz, peracetylated), Tris-GalNAcAc3-Cbz, Tri-β-GalNAcAc3-NHCbz, Triantennary β-GalNAcAc3-NHCbz
O-3020
50mg/$1,300
100mg/$1,900
500 mg/$7,400
CAS # 1159408-63-5
Formula C87H134N10O38
Molecular Weight 1928.04
Purity >95%
Description Triantennary beta-GalNAc, a ligand for asialoglycoprotein receptor (ASGPR), where the sugars are protected by acetylation and the Tris tertiary amine is protected by benzyloxycarbonyloxy (Cbz).
(2R,2’R,3R,3‘R,4R,4’R,5R,5‘R,6R,6’R)-((16-((3-((3-(5-(((3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)pentanamido)propyl)amino)-3-oxopropoxy)methyl)-16-amino-5,11,21,27-tetraoxo-14,18-dioxa-6,10,22,26-tetraazahentriacontane-1,31-diyl)bis(oxy))bis(5-acetamido-2-(acetoxymethyl)tetrahydro-2H-pyran-6,3,4-triyl) tetraacetate trifluoroacetate salt
O-3021
50 mg/$1,400
100 mg/$2,200
500 mg/$8,400
CAS# 1159408-65-7
5-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)pentanoic acid
O-3022
500mg/$700
250mg/$450
Formula C19H29NO11
Molecular Weight 447.43
CAS: 1159408-54-4
Purity >99%
22-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-7,7-bis((3-((3-(5-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)pentanamido)propyl)amino)-3-oxopropoxy)methyl)-5,12,18-trioxo-9-oxa-6,13,17-triazadocosanoic acid
O-3023
100mg/$5,000
50mg/$3,100
CAS # 1637413-46-7
Formula C84H134N10O39
Molecular Weight 1908.03
Purity >95%
1-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-16,16-bis((3-((3-(5-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)pentanamido)propyl)amino)-3-oxopropoxy)methyl)-5,11,18-trioxo-14-oxa-6,10,17-triazanonacosan-29-oic acid
O-3024
CAS# 1426159-34-3
50 mg/$3,500
100 mg/$6,000
Purity >99%
36-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl) tetrahydro-2H-pyran-2-yl)oxy)-21,21-bis((3-((3-(5-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)pentanamido)propyl) amino)-3-oxopropoxy)methyl)-19,26,32-trioxo-4,7,10,13,16,23-hexaoxa-20,27,31-triazahexatriacontanoic acid
O-3025
50 mg/$4,000
100 mg/$7,500
CAS# N/A
Purity In progress
1-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-16,16-bis((3-((3-(5-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2yl)oxy)pentanamido)propyl)amino)-3-oxopropoxy)methyl)-5,11,18-trioxo-14-oxa-6,10,17-triazanonacosan-29-oic acid
CAS# 1953146-81-0
36-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-21,21-bis((3-((3-(5-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)pentanamido)propyl)amino)-3-oxopropoxy)methyl)-19,26,32-trioxo-4,7,10,13,16,23-hexaoxa-20,27,31-triazahexatriacontanoic acid
O-3027
50 mg/$4,000
100 mg/$7,500
Cas# 1953146-81-0
Monodispersed PEG
134-azido-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87,90,93,96,99,102,105,108,111,114,117,120,123,126,129,132-tetratetracontaoxatetratriacontahectan-1-ol
O-3048
sales@organixinc.com for price.
Purity >95%
3,6,9,12,15,18,21,24 27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87,90,93,96,99,102,105,108,111,114,117,120,123,126,129,132-tetratetracontaoxatetratriacontahectan-1,134-diol
sales@organixinc.com for price.
Cas#: 28780-46-3
Purity >95%
1-phenyl-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98,101,104,107,110,113,116,119,122,125,128,131,134-pentatetracontaoxahexatriacontahectan-136-ol
O-3050
sales@organixinc.com for price.
Purity >95%
134-amino-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87,90,93,96,99,102,105,108,111,114,117,120,123,126,129,132-tetratetracontaoxatetratriacontahectan-1-ol
O-3051
sales@organixinc.com for price.
Purity >95%
134-azido-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87,90,93,96,99,102,105,108,111,114,117,120,123,126,129,132-tetratetracontaoxatetratriacontahectan-1-amine
O-3053
sales@organixinc.com for price.
Purity >95%
3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87,90,93,96,99,102,105,108,111,114,117,120,123,126,129,132-tetratetracontaoxatetratriacontahectan-1,134-diamine
O-3054
sales@organixinc.com for price.
Purity >95%
tert-butyl (134-amino3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87,90,93,96,99,102,105,108,111,114,117,120,123,126,129,132-tetratetracontaoxatetratriacontahectyl)carbamate
O-3055
sales@organixinc.com for price.
Purity >95%
3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87,90,93,96,99,102,105,108,111,114,117,120,123,126,129,132-tetratetracontaoxatetratriacontahectanedioic acid
O-3056
sales@organixinc.com for price.
Purity >95%
134-amino-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87,90,93,96,99,102,105,108,111,114,117,120,123,126,129,132-tetratetracontaoxatetratriacontahectanoic acid
O-3057
sales@organixinc.com for price.
Purity >95%
tert-butyl 1-amino-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87,90,93,96,99,102,105,108,111,114,117,120,123,126,129,132-tetratetracontaoxapentatriacontahectan-135-oate
O-3058
sales@organixinc.com for price.
Purity >95%
tert-butyl 1-azido-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87,90,93,96,99,102,105,108,111,114,117,120,123,126,129,132-tetratetracontaoxapentatriacontahectan-135-oate
O-3059
sales@organixinc.com for price.
Purity >95%
Our Product Offerings
Terms of Sale
All products are supplied for research and development purposes only. They are not for human use or consumption, or drug, household, or other uses. Organix warrants that its products conform to their descriptions as provided, however product descriptions are believed to be correct but do not claim to be all inclusive and should be used only as a guide.
No other warranty, express or implied, is granted by the purchase of products from Organix, and Organix shall not be held liable for any damage of any kind resulting from any use of its products. Organix’s liability and Buyer’s remedy shall be limited either to refund of the purchase price excluding shipping charges, or replacement of Organix’s non-conforming product, at Organix’s sole discretion. Such refunded or replacement products must first be accepted by Organix to be non-conforming.
All Products For Research Use Only. Sold under the Hatch-Waxman exemption (safe harbor exemption)
3-((4,4-Bis(octyloxy)butanoyl)oxy)-2-((((3-(diethylamino)propoxy)carbonyl)oxy)methyl)propyl (9Z,12Z)-octadeca-9,12-dienoate
Registry Number 1799316-64-5
100 mg/$5,000
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)