Our Expertise

Custom Organic Synthesis & Medicinal Chemistry Services

 

Accelerate your project from discovery
to the pharmaceutical pipeline with elegant
solutions to complex chemical challenges.

As a US-based Contract Research Organization (CRO) specializing in high-complexity organic and medicinal chemistry, we understand that reliable synthetic chemistry is essential to success. Our mission is to solve the synthetic problems that slow down R&D—leveraging the intellectual capital and technical resources of our organization to advance your program. With Organix,  you are "buying the team rather than the service," ensuring your project is handled by our dedicated US-based scientists.

Global Scale, Local Expertise

Organix operates from a state-of-the-art facility in Woburn, MA. As a company within the Symeres group (an integrated European drug discovery and development company), we embody "The lab next door, wherever you are." This structure provides the agility of a local partner backed by a global network of over 600 scientists. Critically, this integration allows us to deliver integrated solutions spanning from hit finding to clinical proof-of-concept research, providing confidence and convenience by safeguarding your confidential project information within a single partner organization.

  • Precision Synthesis and De-risked Development: We are your scientific problem-solvers. Clients gain direct access to our US-based team of scientists, whose specialized technical expertise and collaborative approach ("Chemistry Family") ensure elegant solutions to your most complex synthetic challenges.

  • The Challenge: Accelerating hit-to-lead and refining Structure-Activity Relationships (SAR) demands rapid, high-quality chemical iteration. 

    The Organix Solution: We specialize in SAR optimization and hit-to-lead studies. Leveraging the power of parallel chemistry, we efficiently generate focused compound libraries  and reference standards from published literature

  • The Challenge: Novel chemical entities (NCEs) and complex architectures often require bespoke, non-standard synthetic routes. 

    The Organix Solution: We deliver complex multi-step synthesis, heterocyclic chemistry, and carbohydrate chemistry. Our Contract R&D excels at optimizing synthetic procedures for reproducibility and scalability and executing challenging transformations such as cross-coupling reactions.

  • The Challenge: The shift to gene therapies (mRNA, siRNA) requires highly specialized, high-purity lipids and delivery vehicles that meet GMP standards. 

    The Organix Solution: We are specialists in lipids and oligonucleotides. We can provide GMP-grade lipids for mRNA and siRNA delivery vehicles, alongside specialized services in GalNAc conjugation technology for targeted delivery and the design of custom polymers with tailored properties for specific drug formulation needs.

  • The Challenge: Verifying compound purity and structure is non-negotiable for regulatory and scientific integrity, demanding advanced analytical rigor and rapid data delivery.

    The Organix Solution: We offer a full range of analytical testing and characterization services essential for quality control and structure elucidation. Our facility is equipped with advanced instrumentation including multinuclear NMR spectroscopy, HPLC, UHPLC-CAD,  and mass spectrometry. This infrastructure, including LC-MS systems, ensures every molecule we deliver meets rigorous standards, often providing Expert Data with Same-day Turnaround

Why Partner with Organix?

Integrated Drug Discovery

As part of Symeres, we align with the brand essence "Making Molecules Matter. Together," offering end-to-end access to a wider network of discovery capabilities from hit finding to clinical proof-of-concept. This structure provides clients with the confidence and convenience of securing confidential project information within a single partner organization.

Ready to accelerate your timeline? Discuss your specific chemistry needs with our team.

The Team Advantage

You are "buying the team rather than the service." We foster personal communication and powerful collaborations, ensuring our US-based scientists act as a committed extension of your internal R&D department.

In addition to contract research, we provide direct access to a catalog of chemistries, including Reference Standards, Drug Impurities, Metabolites, GalNAc dendrimers and Monodispersed PEG. This catalog also includes specialized materials such as Lipids (ask us about our GMP-grade lipid synthesis), supporting the most demanding research and development needs.