Medicinal Chemistry
Services
Driving Drug Discovery and Development
Our medicinal chemistry expertise enables breakthroughs in pharmaceutical innovation:
Hit-to-lead optimization & SAR studies for rapid discovery cycles.
Parallel synthesis & computational chemistry to streamline workflows.
Early ADME services (via our sister company ADMEscope) to enhance compound profiling.
From RNA interference to impurity profiling, our medicinal chemistry CRO services provide comprehensive support for biotherapeutics. Our lipids used in lipid nanoparticles (LNPs) and our polymers used in polymer nanoparticles (PNPs) are highly regarded ingredients used in vaccine research, gene therapy and drug delivery.
Advancing Drug Delivery with Medicinal Chemistry
Organix has a long-standing legacy in medicinal chemistry for drug delivery, including expertise in:
GalNAc Conjugation: Coupling small molecules and lipids to GalNAc dendrimers for targeted delivery.
Bioconjugates: Applying advanced synthesis techniques to conjugate small or large molecules to proteins (such as HRP) and synthetic polymers (such as HPMA polymers).
Controlled Substance Synthesis: Organix has the expertise and is fully licensed to synthesize controlled substances (Schedules I through IV).
Purification & Characterization: Expertise in normal and reverse-phase chromatography for purification and NMR techniques for structural characterization of all organic molecules. Our multinuclear NMR allows advanced 2D-NMR techniques such as proton observed 15N-NMR.
We work closely with you to solve your most challenging synthesis and formulation problems, ensuring high-quality, scalable solutions for your drug delivery needs.
Symegold Library
Organix provides access to Symeres’ Symegold library, a collection of more than 75,000 novel and lead-like compounds for high-throughput screening (HTS). This library of derivatized scaffolds has been carefully designed to cover as much druglike space as possible, whilst maintaining favorable physicochemical properties. Furthermore, the library design principles allow for the expedient synthesis of additional analogues and scaffold hopping can be employed to quickly expand the chemical diversity.
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Medicinal
Chemistry
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Solutions
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Chemistry
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