LP-01 (O-10561)
3-((4,4-Bis(octyloxy)butanoyl)oxy)-2-((((3-(diethylamino)propoxy)carbonyl)oxy)methyl)propyl (9Z,12Z)-octadeca-9,12-dienoate
Registry Number 1799316-64-5
100 mg/$5,000
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
3-((4,4-Bis(octyloxy)butanoyl)oxy)-2-((((3-(diethylamino)propoxy)carbonyl)oxy)methyl)propyl (9Z,12Z)-octadeca-9,12-dienoate
Registry Number 1799316-64-5
100 mg/$5,000
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
3-((4,4-Bis(octyloxy)butanoyl)oxy)-2-((((3-(diethylamino)propoxy)carbonyl)oxy)methyl)propyl (9Z,12Z)-octadeca-9,12-dienoate
Registry Number 1799316-64-5
100 mg/$5,000
For Research Use Only.
Sold under the Hatch-Waxman exemption (safe harbor exemption)
A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing
Cell Reports (2018), 22 (9), 2227-2235
Authors: David V. Morrissey, et al.
Published February 27, 2018
DOI: 10.1016/j.celrep.2018.02.014
LP01 can significantly reduce liver bioaccumulation compared to levels observed with other ionizable lipids such as MC3.