LP-01 (O-10561)

$5,000.00

3-((4,4-Bis(octyloxy)butanoyl)oxy)-2-((((3-(diethylamino)propoxy)carbonyl)oxy)methyl)propyl (9Z,12Z)-octadeca-9,12-dienoate

Registry Number 1799316-64-5

100 mg/$5,000

For Research Use Only.

Sold under the Hatch-Waxman exemption (safe harbor exemption)

3-((4,4-Bis(octyloxy)butanoyl)oxy)-2-((((3-(diethylamino)propoxy)carbonyl)oxy)methyl)propyl (9Z,12Z)-octadeca-9,12-dienoate

Registry Number 1799316-64-5

100 mg/$5,000

For Research Use Only.

Sold under the Hatch-Waxman exemption (safe harbor exemption)

A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing

Cell Reports (2018), 22 (9), 2227-2235

Authors: David V. Morrissey, et al.

Published February 27, 2018

DOI: 10.1016/j.celrep.2018.02.014

LP01 can significantly reduce liver bioaccumulation compared to levels observed with other ionizable lipids such as MC3.