Registry Number 1224606-06-7
Dlin-MC3-DMA also known as MC3, is one of the most utilized cationic lipids that is used for making Lipid Nano-Particles (LNPs). These lipids, can form nanoparticles that can encapsulate and deliver siRNA, mRNA, DNA or small molecules into the cytoplasm and represent the most advanced delivery platforms for systemic administration of active molecules.
Jayaraman M et al. “Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo.” Angew Chem Int Ed Engl. 2012, 51(34), 8529.